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AssigneeQueen Mary University of London
InventorsYaohe Wang, Ming Yuan
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The present invention relates to a vaccinia virus vector comprising a nucleic acid sequence encoding a SCR1-, SCR2-, SCR3-, and SCR4-domain deleted B5R gene (B5R SCR1− SCR2−SCR3− SCR4−) inserted into the TK gene of the vaccinia virus. The invention also relates to compositions comprising the vaccinia virus vector, methods of treatment using the compositions, medical uses of the compositions and kits comprising the vaccinia virus vector. The invention also relates to a nucleic acid sequence encoding a SCR1-, SCR2-, SCR3-, and SCR4-domain deleted B5R gene (B5R SCR1− SCR2− SCR3− SCR4−) of vaccinia virus.
A vaccinia virus vector comprising a nucleic acid sequence encoding a SCR1-, SCR2-, SCR3-, and SCR4-domain deleted B5R gene (B5R SCR1− SCR2− SCR3− SCR4−) inserted into the TK gene of the vaccinia virus.
A nucleic acid sequence encoding a SCR1-, SCR2-, SCR3-, and SCR4-domain deleted B5R gene (B5R SCR1− SCR2− SCR3− SCR4−) of vaccinia virus.
Dependencies are inferred from the claim text.