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US 2021/0330957 A1Published application
Use and monitoring of inhaled nitric oxide with left ventricular assist devices
AssigneeMallinckrodt Pharmaceuticals Ireland Limited
InventorsJim Potenziano, Douglas Alan Greene, Craig Flanagan
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Abstract
Described are systems and methods for administration of nitric oxide (NO) with use of left ventricular assists devices (LVADs), as well as systems and methods for monitoring the NO delivery devices and/or the LVAD.
Claims8
A method of monitoring the left ventricle of a patient with a left ventricular assist device (LVAD), the method comprising:
- reducing the pump speed of the LVAD or turning off the LVAD;
- measuring one or more pulmonary hemodynamic parameters of the patient to obtain a first pulmonary hemodynamic value;
- preloading the left ventricle by administering inhaled nitric oxide to the patient;
- measuring one or more pulmonary hemodynamic parameters of the patient after or during administration of inhaled nitric oxide to obtain a second pulmonary hemodynamic value;
- comparing the one or more hemodynamic parameters to a predetermined range;
- and
- adjusting the dose of inhaled nitric oxide if the one or more hemodynamic parameters are outside of the predetermined range.
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Dependencies are inferred from the claim text.