Methods and apparatus for controlling respiratory therapy

An anti-infection therapy device comprising:

• a pressure generator configured to generate a flow of air at a controllable flow rate to a patient interface;
• and
• a controller configured to:
• compute a target flow rate profile for a patient using a margin function, such that the target flow rate profile exceeds, according to the margin function, a minimum inspiratory flow rate profile of the patient's inspiration;
• and
• control setting of the pressure generator to generate a flow of air to the patient interface according to the target flow rate profile, wherein the generation is in synchrony with a sensed parameter that is indicative of a breathing cycle of the patient.

Anti-infection therapy apparatus comprising:

• means for generating a flow of air at a controllable flow rate to a patient interface;
• means for computing a target flow rate profile for a patient using a margin function, such that the target flow rate profile exceeds, according to the margin function, a minimum inspiratory flow rate profile of the patient's inspiration;
• and
• means for controlling the means for generating to generate the flow of air according to the target flow rate profile, wherein the generation is in synchrony with a sensed parameter that is indicative of a breathing cycle of the patient.