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US 2021/0330874 A1Published application
Multicolumn Blood Plasma Immunomodulating Agents Rebalancing System
AssigneeThompson Oncology Devices LLC
InventorsJoel Wallace Graff, Christopher Armstrong Kay, Randall Jay Daughenbaugh
Life of this patent
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Abstract
Generally, a blood plasma immunomodulating agent rebalancing system. In particular, a blood plasma sTNFR and cytokine rebalancing system and methods of rebalancing sTNFR and cytokines in the blood plasma of a subject during plasmapheresis.
Claims23
An apparatus, comprising:
- a plasmapheresis device;
- a valved conduit adapted to receive blood plasma from said plasmapheresis device, said valved conduit including:
- a valve assembly operable to direct said blood plasma to a soluble TNF receptors removal medium or operable to direct said blood plasma to a cytokine removal medium, said valve assembly operable to direct said blood plasma passed through said TNF receptors removal medium to said subject or operable to direct said blood plasma passed through said cytokine removal medium to said subject,
- wherein said soluble TNF receptor removal medium adapted to remove soluble TNF receptors in blood plasma of a subject,
- wherein said cytokine removal medium adapted to remove cytokines in said blood plasma of said subject, whereby said apparatus rebalances levels of said soluble TNF receptors and said cytokines toward normative levels in said blood plasma of said subject.
2 more elements
23-32. (canceled)
Dependencies are inferred from the claim text.