Collagenase Clostridium Histolyticum Injection Therapies
AssigneeInnoMed Technologies, Inc.
InventorJohn Joseph
Life of this patent
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Abstract
Collagenase Clostridium Histolyticum (EN3835) is a proteinase that can hydrolyze the triple-helical region of collagen under physiological conditions. EN3835 targets the collagenase structural matrix at the site of injection and does not require systemic exposure. Embodiments include methods of lysing subdermal collagen to treat various conditions such as benign prostatic hyperplasia, tracheal stenosis, subglottic stenosis and scleroderma.
Claims19
A method of reducing localized collagen tissue in a patient comprising injection of collagenase clostridium histolyticum at or near the localized collagen tissue.
A method of treating a patient with tracheal stenosis comprising a step of injecting collagenase clostridium histolyticum.
A method of treating a patient with subglottic stenosis comprising injecting collagenase clostridium histolyticum.
A method of treating a patient with esophageal stricture comprising a step of injecting collagenase clostridium histolyticum.
Dependencies are inferred from the claim text.