Methods and compositions for inducing neural plasticity
AssigneeCase Western Reserve University
InventorsJerry Silver, Yu Luo, Fucheng Luo
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Abstract
A method of promoting compensatory plasticity of spared neural cells after a neural injury includes contacting the spared neural cells with an effective amount of a therapeutic agent comprising a therapeutic peptide, wherein the therapeutic peptide comprises an amino acid sequence with at least 70% identity to SEQ ID NO:32.
Claims44
A method of promoting compensatory plasticity of spared neural cells after a neural injury, comprising:
- contacting the spared neural cells with an effective amount of a therapeutic agent comprising a therapeutic peptide, wherein the therapeutic peptide comprises an amino acid sequence with at least 70% identity to SEQ ID NO:32.
A method of treating a neural injury in a subject in need thereof, comprising:
- promoting compensatory plasticity in spared neural cells after the neural injury by administering to the subject an effective amount of a therapeutic agent comprising a therapeutic peptide, wherein the therapeutic peptide comprises an amino acid sequence with at least 70% identity to SEQ ID NO:32.
The method of claim 34, wherein the TBI is a concussion.
The method of claim 34, wherein the ischemia is focal ischemia or global ischemia.
Dependencies are inferred from the claim text.