Polypeptide therapeutics and uses thereof
AssigneeBoard of Regents, The University of Texas System
InventorsRobert O. WILLIAMS, III, Steven IDELL, Sreerama SHETTY
Life of this patent
Estimating the term…
Abstract
Methods and composition for delivery of enzymes to a subject's airway. In some aspects, nebulized composition of enzymes, such as plasminogen activators are provided. In further aspects perfluorocarbon compositions comprising enzymes, such as plasminogen activators are provided. Compositions may, in some aspects, be used for the treatment of lung infections or acute lung injury, such as inhalational smoke induced acute lung injury (ISALI).
Claims30
A method of treating or preventing an injury, infection, or disease of the lungs in a subject comprising administering to the airway of the subject an effective amount of a nebulized solution of a caveolin-1 polypeptide comprising an amino acid sequence of FTTFTVT (SEQ ID NO:
- 1).
Dependencies are inferred from the claim text.