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US 2021/0330671 A1Published application
Phenyloxadiazole derivatives as pgds inhibitors
AssigneeSanofi
InventorsChristopher L. VANDEUSEN, Franz J. WEIBERTH, Harpal S. GILL, George LEE, Andrea HILLEGASS
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Abstract
This invention is directed to a compound of formula (1): wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the compound, intermediates and processes for making said compounds, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma, chronic obstructive pulmonary disease (COPD) and age-related macular degeneration (AMD).
Claims18
A compound of formula (I):
- wherein
- R1 is hydrogen or C1-C3alkyl;
- R2 is hydrogen, halogen or C1-C3alkyl;
- and
- R3 is hydroxy alkyl;
- or a pharmaceutically acceptable salt thereof.
3 more elements
A compound of formula
- or an acid addition salt thereof.
-24. (canceled)
Dependencies are inferred from the claim text.