Pharmaceutical compositions

A composition comprising a crystal form of a compound of Formula I:

• wherein R1 is hydrogen;
• C1-C10 straight chain or branched chain substituted or unsubstituted alkyl, wherein the substituent is C3-C6 cycloalkyl or C3-C6 cycloalkyl substituted by straight chain or branched chain C1-C4 alkyl;
• straight chain or branched chain C2-C10 alkenyl;
• or substituted straight chain or branched chain C2-C10 alkenyl, wherein the substituent is C3-C6 cycloalkyl or C3-C6 cycloalkyl substituted by straight chain or branched chain C1-C4 alkyl;
• C1-C6 hydroxyalkyl;
• alkoxyalkyl wherein the alkoxy moiety contains one to about four carbon atoms and the alkyl moiety contains one to about six carbon atoms;
• acyloxyalkyl wherein the acyloxy moiety is alkanoyloxy of two to about four carbon atoms or benzoyloxy, and the alkyl moiety contains one to about six carbon atoms;
• benzyl;
• (phenyl)ethyl;
• or phenyl;
• the benzyl, (phenyl)ethyl, or phenyl substituent being optionally substituted on the benzene ring by one or two moieties independently selected from C1-C4 alkyl, C1-C4 alkoxy, or halogen, with the proviso that if the benzene ring is substituted by two moieties, then the moieties together contain no more than six carbon atoms;
• R2 and R3 are independently selected from hydrogen, C1-C4 alkyl, phenyl, or substituted phenyl, wherein the substituent is C1-C4 alkyl, C1-C4 alkoxy, or halogen;
• X is C1-C4 alkoxy, alkoxyalkyl wherein the alkoxy moiety contains one to about four carbon atoms and the alkyl moiety contains one to about four carbon atoms, C1-C4 hydroxyalkyl, C1-C4 haloalkyl, alkylamido wherein the alkyl group contains one to about four carbon atoms, amino, substituted amino wherein the substituent is C1-C4 alkyl or C1-C4 hydroxyalkyl, azide, chloro, hydroxy, 1-morpholino, 1-pyrrolidino, or C1-C4 alkylthio;
• and
• R is hydrogen, straight chain or branched chain C1-C4 alkoxy, halogen, or straight chain or branched chain C1-C4 alkyl;
• and
• wherein the crystal form is a hydrochloric acid salt, a sulfate salt, a phosphate salt, a maleate salt, a malate salt, an adipate salt, a glycolate salt, a hippurate salt, a tartrate salt, a fumarate salt, a citrate salt, a lactate salt, a succinate salt, a tosylate salt, mesylate salt, an oxalate salt, a gentisate salt, a benzoate salt, or a nitrate salt in crystalline form A, B, C, D, E, F or G.