Rivastigmine patch for long-term administration

A rivastigmine patch for transdermal treatment comprising a backing film;

• a rivastigmine matrix layer comprising rivastigmine or a pharmaceutically acceptable salt thereof;
• a self-adhesive matrix layer comprising an adhesive that adheres to the skin;
• and a release liner that is removed before use,
• wherein the content per patch area of the rivastigmine or a pharmaceutically acceptable salt thereof is 2 to 15 mg/cm2 based on the rivastigmine free base, and
• the rivastigmine matrix layer comprises hydrophobic silica.