S-enantiomerically enriched compositions of beta blockers for treating amyotrophic lateral sclerosis
AssigneeActimed Therapeutics Limited
InventorsAndrew J.S. COATS, Stefan ANKER, Jochen SPRINGER
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Abstract
The present invention relates to S-enantiomerically enriched compositions of beta blockers and uses thereof, including uses of the beta blocker compositions for treating amyotrophic lateral sclerosis. The beta blocker compositions can also be used for preventing loss of lean mass, preventing body weight loss in subjects, improving quality of life in subjects, and prolonging survival in amyotrophic lateral sclerosis patients. The beta blocker can be oxprenolol or a pharmaceutically acceptable salt thereof.
Claims16
A method of increasing locomotive activity in an individual having amyotrophic lateral sclerosis, comprising administering to the individual an effective amount of a composition comprising a beta blocker which is oxprenolol or a pharmaceutically acceptable salt thereof, wherein the composition is enantiomerically enriched for the S-enantiomer of the beta-blocker.
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Dependencies are inferred from the claim text.