Compounds and compositions for use
AssigneeDr Weller Limited
InventorMike Finnen
Life of this patent
Estimating the term…
Abstract
The present disclosure provides compounds and compositions which may be used to augment, supplement and/or replace the products of certain UV sensitive/dependent processes. In particular, the disclosure provides sunscreen compositions which avoid problems associated with prior art sunscreen compositions which inhibit the natural progression of certain in vivo sunlight/UV dependent processes including processes which result in Nitric Oxide/Vitamin D production in the skin.
Claims18
A method of treating or preventing diseases associated with reduced, impaired or inhibited nitric oxide (NO) and/or vitamin D production, said method comprising administering to a subject in need thereof a composition comprising:
- (i) a thiol compound and/or a disulfide;
- and
- (ii) a NO-precursor compound.
A method of augmenting or stimulating nitric oxide (NO) and/or vitamin D3 production in a subject wearing or using a sunscreen composition, said method comprising using, applying or administering a sunscreen composition comprising:
- (i) a thiol compound and/or a disulfide;
- and
- (ii) a NO-precursor compound.
A method of providing a sunscreen composition which:
- (i) does not substantially inhibit NO and/or vitamin D production in a user;
- and/or
- (ii) which facilitates, enhances, induces and/or stimulates a level of vitamin D and/or NO production in a user;
- said method comprising supplementing a sunscreen composition with one or more compounds selected from the group consisting of:
- (i) a compound which upon exposure to sunlight (or the UV component thereof), generates NO or an intermediate or metabolite which can be used to generate NO in vivo;
- (ii) a thiol compound;
- (iii) a disulfide;
- (iv) a compound which upon exposure to sunlight (or the UV component thereof), generates vitamin D or an intermediate or metabolite which can be used to generate active vitamin D in vivo;
- and
- (iv) 7-dehydrocholesterol.
Dependencies are inferred from the claim text.