Devices, systems, and methods for protecting healthcare workers from airborne pathogens

An isolation barrier comprising:

• a mask comprising a face opening adapted to rest against the subject's face around a subject's nose and mouth and an access opening opposite to the face opening, the access opening being arranged and configured to be in front of the subject's nose and/or mouth when the mask rests on the subject's face and to provide access to the subject's nose and/or mouth, the mask extending away from the face opening to the access opening to form an interior mask volume between the access opening and the face opening;
• a feature adapted to hold the mask on the subject's face;
• and
• an enclosure comprising a first enclosure opening attached around the access opening, a second enclosure opening, and an enclosure volume extending between the first and second enclosure openings, the interior mask volume and enclosure volume defining a medical procedure field configured to extend from the subject's nose and mouth to the second enclosure opening when the isolation barrier is in place on the subject's face.