System and methods for use in vision assessment to determine refractive errors and neurodegenerative disorders by ocular biomarking features

A method of operating a diagnostic device for performing a neurodegenerative disease screening exam, the diagnostic device including a display configure to render dynamically adjusted, binocular or dichoptic visual stimuli to a user, a varifocal optics system orientated between the display and the user's eyes, an eye tracking system configured to track movement of the user's eyes, and a processor, the meth-od including the processor executing the algorithm steps of:

• adjusting the varifocal optics system to an initial refractive correction;
• displaying visual stimuli on the display based on desired test procedure;
• collecting eye movement data using eye tracking system;
• and
• determining neurodegenerative disease by comparing collected eye movement data with baseline eye movement data associated with desired test scenario.

A method of operating a diagnostic device for performing a refractive errors assessment, the diagnostic device including a display configure to render dynamically adjusted, binocular or dichoptic visual stimuli to a user, a varifocal optics system orientated between the display and the user's eyes, an ocular reflex analyzer emitting light signals towards the user's eye s and obtaining light signal reflected from selected part of the eye to measure eye accommodation during an on-going visual stimulation, an eye tracking system configured to track movement of the user's eyes, and a processor, the method including the processor executing the algorithm steps of:

• displaying visual stimuli on the display based on desired refractive errors assessment test procedure;
• collecting eye movement data using eye tracking system;
• collecting ocular accommodation data using the ocular reflex analyzer;
• and
• determining best refractive correction and ocular behavior based on collected eye movement data and ocular behavior data.