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AssigneeIRP Health Pty Ltd
InventorsDavid Xiang YU, Zhicheng XIAO, Colin William POUTON, Zhiyong HE
Estimating the term…
This invention relates to berberine alkaloids, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals, particularly Lawsonia infection. In particular, the invention relates to berberine alkaloids, formulations thereof, and their application as antimicrobial agents in the prevention and/or treatment of infectious disease including bacterial, viral, parasitic or fungal infections, and for improving feed conversion ratio in food-producing animals. Also described is the use of berberine alkaloids as feed preservatives, added to feed compositions, and used in combination with further agents suitable for treating infectious disease.
A method of preserving an animal feed comprising incorporating a berberine alkaloid in the feed in an amount of 0.001 g/kg to 2 g/kg of a solid feed or in an amount of 0.001 g/L to 0.1 g/L of a liquid feed.
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An animal feed comprising a berberine alkaloid as a feed preservative in an amount of 0.001 g/kg to 2 g/kg of a solid feed or in an amount of 0.001 g/L to 0.1 g/L of a liquid feed.
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The animal feed of claim 58 further comprising any one or more of antimicrobial compounds selected from the group consisting of arecoline, baicalin, baicalein, anemonin, matrine, oxymatrine, andrographolide, piceid, honokiol and thymol.
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A method for the prevention and/or treatment of an infectious disease in an animal caused by bacteria from the genus Lawsonia, wherein the method comprises administering an effective amount of a berberine alkaloid or a composition comprising a berberine alkaloid and any one or more of the antimicrobial compounds selected from the group consisting of arecoline, baicalin, baicalein, anemonin, matrine, oxymatrine, andrographolide, piceid, honokiol and thymol.
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A method for the reduction of feed conversion ratio in a food-producing animal, comprising feeding the animal with a feed according to claim 58.
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Dependencies are inferred from the claim text.