Lateral flow assay for assessing recombinant protein expression or reporter gene expression
AssigneeQoolabs, Inc.
InventorHong Qi
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Abstract
The present disclosure relates to lateral flow test devices, and uses thereof, for assessing recombinant protein (polypeptide) expression or reporter gene expression in a sample. In some aspects, the present disclosure relates to the use of lateral flow immunoassay to quickly detect the expression of recombinant proteins. In some aspects, lateral flow immunoassay can be used for qualitative and/or quantitative analysis of the recombinant protein expression.
Claims37
A lateral flow test device for assessing recombinant protein (polypeptide) expression or reporter gene expression in a sample, which device comprises a porous matrix that comprises a test location on said porous matrix, said test location comprising a test reagent that binds to an analyte or another binding reagent that binds to said analyte, or is an analyte or an analyte analog that competes with an analyte in said sample for binding to a binding reagent for said analyte,
- wherein said analyte is a recombinant protein (polypeptide) expression product or a reporter gene expression product, and
- wherein a liquid sample flows laterally along said test device and passes said test location to form a detectable signal to determine the presence, absence and/or amount of said recombinant protein (polypeptide) expression product or said reporter gene expression product in said sample.
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Dependencies are inferred from the claim text.