Methods of detection of compound, antibody or protein using recombinant endospores or bacteria as sensing element
AssigneeNational Taipei University of Technology
InventorShao-Yi HOU
Life of this patent
Estimating the term…
Abstract
The present invention provides a method and a system for detecting the presence of an analyte in a sample. In particular, the present invention provides a system, such as a diagnostic kit, for detecting the presence of an analyte in a sample, comprising (a) a recombinant bacterium or spore expressing one or more recombinant proteins on the surface thereof, wherein the recombinant protein specifically binds to the analyte directly or through a binding agent that specifically binds to the recombinant protein and the analyte, and (b) a signal-producing substance that can be detected.
Claims24
A system for detecting the presence of an analyte in a sample, comprising (a) a recombinant bacterium or spore expressing one or more identical or different recombinant proteins on the surface thereof, wherein the recombinant protein specifically binds to the analyte directly or through a binding agent that specifically binds to the recombinant protein and the analyte, and (b) a signal-producing substance that can be detected, and wherein the system is a diagnostic kit.
(canceled)
(canceled)
Dependencies are inferred from the claim text.