Method and apparatus for in-vitro tissue cultivation

An apparatus for in-vitro tissue cultivation, the apparatus comprising

• a bioreactor chamber configured to contain a medium;
• a scaffold holder which is suspended in the bioreactor chamber and which is configured to receive a seeded-scaffold;
• a rotation mechanism as a stimulator for tissue growth, wherein the bioreactor chamber is coupled to the rotation mechanism, and wherein the rotation mechanism is configured to rotate the bioreactor chamber about two orthogonal axes based on a predetermined motion cycle;
• and
• at least one other stimulator for tissue growth, wherein the at least one other stimulator is configured to apply at least one other stimulation to the seeded-scaffold, and wherein the at least one other stimulator is coupled to the bioreactor chamber.