Process for producing microemulsion system of nano essential oil

A process for producing a microemulsion system of nano essential oil comprising the following steps:

• (i) preparing a dispersed phase by heating an essential oil to a temperature between 60 and 100° C.;
• (ii) preparing a carrier by heating a mixture of diethylene glycol monoethyl ether and lecithin at the weight ratio of between 5:1.5 and 6:1 to a temperature ranging from 60 to 100° C. under vacuum by using a rotary vacuum evaporator system, followed by cooling the mixture to 30° C., then respectively ultrasonicating for 30 minutes, magnetic stirring, and heating at temperature from 60 to 100° C. within 30 minutes, collecting the solution ang introducing into the rotary vacuum evaporator system, and continuing to stir at 100° C.;
• (iii) adding the carrier to the dispersed phase at the weight ratio of between 2:1.5 and 2:1 while keeping the dispersed phase temperature between 60 and 100° C. after addition the carrier, while simultaneously stirring at a rate ranging from 400 and 800 rpm under vacuum;
• then passing the entire solution mixture through a system of a high-pressure homogeneous machine integrated with a dispersion nozzle;
• (iv) adding the solution mixture obtained in step (iii) to Capryol 90 (propylene glycol monocaprylate) at the weight ratio of between 4:1.5 and 4.5:1 while keeping the mixture temperature between 60 and 100° C. after the addition of Capryol 90, then stirring at a rate ranging from 400 to 800 rpm under vacuum;
• (v) preparing microemulsion system of nano essential oil by cooling the mixture to 25° C., homogenizing the mixture by ultrasonication using an ultrasonic homogenizer over a period from 30 to 60 minutes to achieve the a droplet size smaller than 100 nm, controlling the quality of the resultant product by dissolution in water and measurement of the transparency, in which if the required transparency is not met, continue to heat and measure the transparency every 30 minutes until the required transparency is met, stopping the reaction, and performing emulsifying on the solution mixture in an emulsifying device at a stirring rate ranging from 400 to 800 rpm to obtain the microemulsion system of nano essential oil.