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US 2021/0277078 A1Published application
Fiber assembly and use thereof
AssigneeNational University Corporation Hokkaido University
InventorAkira Kakugo
Life of this patent
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Abstract
A fiber assembly includes multiple fibers and nucleic acid fragments that crosslink the multiple fibers, and the fibers are microtubules or actin fibers.
Claims17
A fiber assembly, comprising:
- multiple fibers;
- and
- nucleic acid fragments that crosslink the multiple fibers,
- wherein the fibers are microtubules or actin fibers.
1 more element
A method of producing a fiber assembly,
- wherein the fibers are microtubules or actin fibers,
- the production method includes bringing a first fiber to which a first single-stranded nucleic acid fragment is bound, a second fiber to which a second single-stranded nucleic acid fragment is bound, and a third single-stranded nucleic acid fragment including a region complementary to the first single-stranded nucleic acid fragment and a region complementary to the second single-stranded nucleic acid fragment into contact with each other.
A method of dissociating a fiber assembly into single fibers,
- wherein the fibers are microtubules or actin fibers,
- wherein the fiber assembly includes a first fiber to which a first single-stranded nucleic acid fragment is bound, a second fiber to which a second single-stranded nucleic acid fragment is bound, and a third single-stranded nucleic acid fragment including a region complementary to the first single-stranded nucleic acid fragment and a region complementary to the second single-stranded nucleic acid fragment, and
- wherein the method includes bringing a fourth single-stranded nucleic acid fragment including a region complementary to the third single-stranded nucleic acid fragment into contact with the fiber assembly.
A method of moving a fiber assembly,
- wherein the fibers are microtubules or actin fibers,
- wherein the fiber assembly includes a first fiber to which a first single-stranded nucleic acid fragment is bound, a second fiber to which a second single-stranded nucleic acid fragment is bound, and a third single-stranded nucleic acid fragment including a region complementary to the first single-stranded nucleic acid fragment and a region complementary to the second single-stranded nucleic acid fragment, and
- wherein the method includes bringing the fiber assembly and adenosine triphosphate (ATP) into contact with each other on a substrate whose surface is covered with motor proteins.
Artificial muscles, comprising:
- multiple microtubules;
- and
- kinesin or dynein multimers that crosslink the multiple microtubules.
Dependencies are inferred from the claim text.