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AssigneeNational Institutes for Food and Drug Control
InventorsLan He, Jing Xiong, Xiangxiang Wu, Xin Zhu, Zhonglin Lu, Yan Shi, Na Zhang, Yang Liu
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The present invention relates to a cocrystal of progesterone, which is formed by the active ingredient progesterone and a cocrystal former which is selected from isophthalic acid, 4-formylbenzeneboronic acid and 3-nitrophthalic acid. The present invention also relates to the method for preparing the cocrystal of progesterone and use thereof for increasing the thickness of endometrium, improving progesterone's solubility or increasing progesterone's permeation rate.
A cocrystal of progesterone, characterized in that the cocrystal of progesterone is formed by the active ingredient progesterone and a cocrystal former which is selected from the group consisting of isophthalic acid, 4-formylbenzeneboronic acid and 3-nitrophthalic acid.
Dependencies are inferred from the claim text.