Blood pressure regulation system for the treatment of neurologic injuries

A system for reducing blood pressure variability in a patient, the system comprising:

• an endovascular catheter comprising an expandable element configured to be positioned within an aorta of the patient, a proximal blood pressure sensor disposed on a first side of the expandable element and a distal blood pressure sensor disposed on a second, opposite side of the expandable element;
• one or more processors;
• and
• one or more hardware storage devices having stored thereon computer-executable instructions which are executable by the one or more processors to cause the system to at least:
• obtain a plurality of blood pressure measurements over time from the proximal and distal blood pressure sensors;
• based on the plurality of blood pressure measurements, determine a blood pressure variability metric and a blood pressure;
• determine whether the blood pressure variability metric exceeds a variability threshold;
• upon determining that the blood pressure variability metric exceeds the variability threshold, adjust a size of the expandable element of the endovascular catheter to decrease blood pressure variability;
• determine whether the blood pressure exceeds a ceiling threshold, falls below a floor threshold, or falls outside a predefined blood pressure range;
• and
• upon determining that the blood pressure exceeds the ceiling threshold, falls below the floor threshold, or falls outside the predefined blood pressure range, deliver a medication to decrease or increase blood pressure.