External dressing as well as preparation method and application thereof
OwnerJun CAIinventor
Life of this patent
Estimating the term…
Abstract
The present invention relates to an external dressing as well as a preparation method and application thereof. The external dressing includes: A. a solvent, which is a mixture including normal saline and an HP value regulator, B. a natural polymer as a thickener; and C. urokinase, the content of which is 0.05-50,000 U/ml. Experiments in mice prove that the present invention has obvious curative effect on wound rehabilitation, and has the advantages of easy realization and operation, fewer side effects and benefit for popularization and application.
Claims10
An external dressing, comprising:
- A. a solvent, wherein the solvent contains a sodium chloride solution, and the content of sodium chloride is 0.9% of the total weight of the external dressing;
- B. a natural polymer, which comprises any one or more of the following components:
- chitosan, cellulose, hyaluronic acid, collagen and sodium alginate,
- wherein the molecular weight of chitosan is 40,000-70,000;
- the weight ratio of the chitosan to the finished external dressing is 5%±2%;
- the weight ratio of the cellulose to the solvent is not greater than 5%;
- the weight ratio of the hyaluronic acid to the solvent is not greater than 2%;
- the weight ratio of the collagen to the solvent is not greater than 0.05%;
- the weight ratio of the gelatin to the solvent is not greater than 5%;
- and the weight ratio of the sodium alginate to the solvent is not greater than 2%;
- and
- C. urokinase, the content of which is 0.05-50,000 U/ml.
An application of the urokinase-containing external dressing, the external dressing containing a solvent and the urokinase, wherein the solvent of the finished external dressing contains sodium chloride accounting for 0.9% by weight of the external dressing;
- the content of the urokinase in the finished external dressing is 0.05-50,000 U/ml;
- the external dressing is applied to therapy of skin wounds;
- and the skin wounds comprise common trauma wounds, burn wounds, refractory wounds, diabetic wounds and pressure sore wounds.
Dependencies are inferred from the claim text.