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US 2021/0275638 A1Published application
Polyhedrin-based slow release growth factor system for neuroprotection of retinal ganglion cell neurons
AssigneesThe Schepens Eye Research Institute, Inc., Cell Guidance Systems Limited
InventorsJulia Oswald Clifton, Christian Pernstich, Petr Baranov, Michael Jones
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Abstract
Described herein are polyhedrin-based slow release growth factor systems and methods of use thereof for neuroprotection of host and donor retinal ganglion cell neurons.
Claims15
A method of treating an optic neuropathy associated with neurodegeneration in the eye and loss of retinal ganglion cells (RGCs), the method comprising administering to an affected eye of the subject a therapeutically effective amount of a composition comprising complexes of one or more growth factors attached to polyhedra comprising polyhedrin protein.
Dependencies are inferred from the claim text.