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AssigneeMicrobiotica Limited
InventorsMatthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris, Ghaith Bakdash, Amy Popple, Dominika Klisko
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The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
A method for treating cancer in a subject in need thereof, comprising administering a composition comprising isolated bacteria selected from at least two species wherein the bacteria from the first species comprise a 16S rDNA sequence having at least 98.7% sequence identity with a nucleic acid sequence according to SEQ ID NO:
Dependencies are inferred from the claim text.