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US 2021/0275562 A1Published application
Cancer treatment methods
OwnerDennis W. Staceyinventor
Life of this patent
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Abstract
A cancer treatment method includes administering a first dose of a drug selectively targeting cells in a particular phase (e.g., S phase cells); and administering an additional dose of the drug after waiting a full normal cell cycle. The method takes advantage of the uniformity of cell cycle length in normal cells (e.g., normal small intestine cells) and the and the lack of this uniformity, or variation in cell cycle length of cancer cells.
Claims20
A method for selectively killing cells in S phase, the method comprising:
- administering a first dose of a drug selectively targeting S phase cells;
- and
- administering an additional dose of the drug after waiting a full normal cell cycle.
A process for treating small intestine cancer comprising in sequence:
- administering a first dose of a drug selectively targeting S phase cells, wherein the drug kills cancer cells in the S phase and normal small intestine cells in the S phase and wherein the drug does not kill cells that are not in the S phase;
- waiting a full normal small intestine cell cycle;
- and administering an additional dose of the drug.
A cancer treatment method comprising:
- administering a first dose of a drug selectively targeting M phase cells;
- and administering an additional dose of the drug after waiting a full normal cell cycle.
Dependencies are inferred from the claim text.