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US 2021/0275514 A1Published application
Compounds for use in treating kidney disorders
AssigneeHoffmann-La Roche Inc.
InventorAlessia FORNONI
Life of this patent
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Abstract
The present disclosure relates to ABCA1 inducer compounds for use in treating kidney disorders, and in particular, chronic kidney diseases, glomerular diseases or proteinuric kidney diseases such as Alport syndrome, focal segmental glomerulosclerosis, and diabetic kidney disease.
Claims28
A compound for treating a kidney disease, wherein said compound is an ABCA1 inducer compound or a pharmaceutically acceptable salt thereof.
A compound:
- 5-(3,4-dichloro-phenyl)-N-((1R,2R)-2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinamide, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.