Compositions and methods of treatment
OwnerChristine Ridden, John Ridden +1inventors
InventorsChristine Ridden, John Ridden, David Cook
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Abstract
The present invention relates to compositions for use in the treatment of a dermatological condition, comprising a polymer capable of forming nanoparticles an anti-inflammatory and/or analgesic agent. The composition is particularly suited to the treatment of acne and/or atopic dermatitis. The invention also relates to novel uses of polyhexamethylene biguanide.
Claims17
A composition for use in the treatment of a dermatological condition, comprising a polymer capable of forming nanoparticles and an anti-inflammatory and/or analgesic agent.
The composition as claimed in any preceding claim, wherein the nanoparticles are formed with and/or in the presence of the anti-inflammatory and/or analgesic agent.
The composition as claimed in any preceding claim, wherein the anti-inflammatory agent comprises a non-steroidal anti-inflammatory (NSAID) agent.
The composition as claimed in any preceding claim, wherein the anti-inflammatory agent comprises one or more selected from the following:
- Rapamycin, Tacrolimus, Ibuprofen, Ciclosporin, Diclofenac, Naproxen and related derivatives and salts thereof.
The composition as claimed in any preceding claim, wherein the composition further comprises one or more of the following component:
- buffers, excipients, binders, oils, water, emulsifiers, glycerin, antioxidants, preservatives and fragrances.
The composition as claimed in any preceding claim, wherein the composition is in the form of a topical medicament.
The composition as claimed in any preceding claim, wherein the dermatological condition comprises acne and/or atopic dermatitis or related conditions.
A composition as claimed in any preceding claim, wherein the composition is in the form of a cream, ointment, spray, powder, foam or mousse.
Use of polyhexamethylene biguanide (PHMB) to form one or more nanoparticles with, or associated with, an anti-inflammatory and/or analgesic agent in the preparation of a medicament for the treatment of a dermatological condition.
A method of producing a composition for the treatment of a dermatological condition comprising mixing a polymer capable of forming nanoparticles with an anti-inflammatory and/or analgesic agent under conditions suitable to allow the formation of nanoparticles.
Dependencies are inferred from the claim text.