Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof

A compound of formula (I):

• or a tautomeric or a stereochemically isomeric form, a pharmaceutically acceptable salt or a solvate thereof, wherein:
• R1 represents C1-6 alkyl, C1-6 alkoxy, C1-6 alkanol, —X—C3-8 cycloalkyl, haloC1-6 alkyl, aryl, heterocyclyl or heteroaryl, wherein said cycloalkyl, aryl, heterocyclyl or heteroaryl groups may be optionally substituted by one or more (e.g. 1, 2, 3 or 4) Ra groups;
• Ra represents C1-6 alkyl, halogen, haloC1-6 alkyl, hydroxy, cyano, nitro, oxo, CONRxRy or C3-8 cycloalkyl;
• Rx and Ry independently represent hydrogen or C1-6 alkyl;
• X represents a bond, —CH2— or —(CH2)2—;
• R2 represents halogen, haloC1-6 alkyl or cyano;
• n represents an integer selected from 0 to 4;
• R3 represents hydrogen, C1-6 alkyl, —X—C3-8 cycloalkyl, haloC1-6 alkyl or —X-aryl,
• wherein said alkyl may be optionally substituted by one or more cycloalkyl groups,
• wherein said cycloalkyl may be optionally substituted by one or more C1-6 alkyl, C1-6 alkoxy, haloC1-6 alkyl, halogen, hydroxy or cyano groups,
• wherein said haloalkyl may be optionally substituted by one or more hydroxy groups,
• wherein said aryl may be optionally substituted by one or more halogen groups,
• wherein R3 and R4 together with the nitrogen atom to which they are attached may join to form a heterocyclyl ring optionally substituted by one or more C1-6 alkyl, haloC1-6 alkyl, or halogen;
• R4 represents hydrogen, C1-6 alkyl or C3-8 cycloalkyl;
• R5 represents C1-6 alkyl or —X-aryl;
• and
• m represents an integer selected from 0 to 4, such that when m represents 2, said R5 groups may join to form a C3-8 cycloalkyl group.