Novel compound isolated from cervi parvum cornu, and pharmaceutical uses thereof
AssigneeFng Research Co., Ltd.
InventorsYoung Sam GOO, Ki Nam SON
Life of this patent
Estimating the term…
Abstract
The present disclosure provides a pharmaceutical composition for the prevention or treatment of inflammatory diseases, leukopenia or neutropenia and a method for synthesizing the same, the pharmaceutical composition including as an active ingredient at least one selected from compounds represented by the Formulas 1 to 4.
Claims13
A pharmaceutical composition for the prevention or treatment of inflammatory diseases, leukopenia or neutropenia, comprising as an active ingredient at least one selected from compounds represented by the following Formulas 1 to 4.
A health functional food for preventing or improving inflammatory diseases comprising compounds represented by the following Formulas 1 to 4 as an active ingredient
A method for synthesizing 1-palmitoyl-2-conjugated linoleoyl-3-acetyl glycerol (PCA glycerol) comprising the steps of:
- (a) reacting palmitic acid with a compound represented by the following Formula 5 under basic conditions to synthesize 1-palmitoyl glycerol;
- (b) reacting the 1-palmitoyl glycerol with acetyl halide under basic conditions to synthesize 1-palmitoyl-3-acetyl glycerol;
- and
- (c) reacting the 1-palmitoyl-3-acetyl glycerol with conjugated linoleic acid under basic conditions.
- (wherein, R1 and R2 are each independently a C1˜C3 alkyl group.)
A method for synthesizing 1-conjugated linoleoyl-2-palmitoyl-3-acetyl glycerol (CPA glycerol) comprising the steps of:
- (a) reacting conjugated linoleic acid with a compound represented by the following Formula 5 under basic conditions to synthesize 1-conjugated linoleoyl-glycerol;
- (b) reacting the 1-conjugated linoleoyl-glycerol with acetyl halide under basic conditions to synthesize 1-conjugated linoleoyl-3-acetyl glycerol;
- and
- (c) reacting the 1-conjugated linoleoyl-3-acetyl glycerol with palmitic acid under basic conditions.
- (wherein, R1 and R2 are each independently a C1˜C3 alkyl group.)
Dependencies are inferred from the claim text.