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AssigneeKyungpook National University Industry-Academic Cooperation Foundation
InventorsKyoung Ho SUK, Jong Heon KIM, Jin HAN
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The present invention relates to a composition for treating neuroinflammatory disease comprising a complement component 8 gamma protein or a fragment thereof, and more particularly, to use for treating neuroinflammatory disease of a complement component 8 gamma protein or a fragment thereof which exhibits an effect of reducing the expression of inflammatory cytokines in microglia. The composition of the present invention has effects of reducing Alzheimer's abnormal behavior patterns and reducing the secretion of neuroinflammatory cytokines in brain microglia and thus can be very usefully used for development of an agent for preventing or treating neuroinflammatory disease.
1-11. (canceled)
A method for preventing, improving or treating neuroinflammatory disease, the method comprising administering an effective dose of a composition comprising a complement component 8-gamma protein or a fragment thereof as an active ingredient to a subject in need thereof.
(canceled)
A method for preventing, improving or treating neuroinflammatory disease, the method comprising administering an effective dose of a composition comprising a vector containing a polynucleotide encoding a complement component 8-gamma protein or a fragment thereof or a cell containing the vector as an active ingredient to a subject in need thereof.
Dependencies are inferred from the claim text.