Method for treating cancer
AssigneeEpizyme, Inc.
InventorHeike KEILHACK
Life of this patent
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Abstract
The present invention provides a method for treating or alleviating a symptom of a disorder, e.g., immune evasion, cancer-cell induced immune dysfunction, reduced immune response, lowered inflammation, decreased expression of a major histocompatibility complex (MHC), or cancer, characterized by aberrant, misregulated, or increased Enhancer of Zeste Homolog 2 (EZH2) activity in a cell or subject in need thereof by contacting the cell or administering to the subject a therapeutically effective amount of an EZH2 inhibitor.
Claims24
-2. (canceled)
A method for boosting an immune response in a subject in need thereof comprising a step of administering to the subject a therapeutically effective amount of an EZH2 inhibitor.
(canceled)
A method for increasing inflammation in a subject in need thereof comprising a step of administering to the subject a therapeutically effective amount of an EZH2 inhibitor.
A method for treating a cancer or a cell proliferative disorder in a subject in need thereof comprising a step of administering to the subject a therapeutically effective amount of an EZH2 inhibitor.
-9. (canceled)
(canceled)
Dependencies are inferred from the claim text.