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US 2021/0267902 A1Published application
Pharmaceutical compositions
AssigneeBoehringer Ingelheim International GmbH
InventorsMasanori ITO, Kenji EGUSA, Roman MESSERSCHMID, Peter SCHNEIDER
Life of this patent
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Abstract
The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and/or a SGLT-2 inhibitor drug, and metformin XR, processes for the preparation thereof, and their use to treat certain diseases.
Claims16
A pharmaceutical composition comprising:
- a) an inner extended release core, wherein the inner extended release core is a formulation comprising metformin hydrochloride, a swellable and/or extended release polymer, and one or more further excipients;
- b) an intermediate seal coating;
- and
- c) an outer immediate release coating, wherein the outer immediate release coating is a film coat formulation comprising 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a film-coating agent, a plasticizer, and, optionally, a glidant.
1 more element
Dependencies are inferred from the claim text.