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US 2021/0263025 A1Published application
Micro-separation for multiplexing
AssigneeFemtoDx
InventorsJiangang John Du, Robert DiNello, Pritiraj Mohanty
Life of this patent
Estimating the term…
Abstract
Articles and systems for separating micro-sized analytes.
Claims25
A capillary tube, comprising:
- a first section located within the capillary tube, the first section comprising a first material;
- a plurality of species-binding entities attached to the first material;
- and
- a sensor adjacent to at least some of the plurality of species-binding entities.
1 more element
A capillary tube, comprising:
- a first section located within the capillary tube, the first section comprising a first material;
- a first plurality of species-binding entities attached to the first material,
- wherein the plurality of species-binding entities are configured to selectively release from the first material;
- and
- a sensor proximate to a distal end of the capillary tube.
2 more elements
A capillary tube, comprising:
- a first section located within the capillary tube, the first section comprising:
- a first material;
- and
- a first plurality of species-binding entities attached to the first material, wherein the first plurality of species-binding entities is configured to selectively release from the first material;
- a second section located within the capillary tube, the second section comprising a second material, wherein the second material is different than the first material and configured to prevent attachment of the first plurality of species-binding entities;
- a third section comprising a second plurality of species-binding entities configured to selectively bind a species, the species bound to the first plurality of species-binding entities;
- and
- a sensor adjacent to at least some of the second plurality of species-binding entities.
5 more elements
The capillary tube of the preceding claim, further comprising a third plurality of species-binding entities.
17-18. (canceled)
A system, comprising:
- a capillary tube comprising a proximal end and a distal end,
- wherein the capillary tube comprises a plurality of species-binding entities attached to at least a first section of the capillary tube;
- a first electrode proximate the proximal end;
- a second electrode;
- and
- a power supply connected to the first electrode and the second electrode.
3 more elements
20-24. (canceled)
A system, comprising:
- an inlet tube;
- a junction fluidically connected to the inlet tube;
- and
- a first outlet tube, a second outlet tube, and a third outlet tube each fluidically connected to the junction,
- wherein the inlet tube, the first outlet tube, the second outlet tube, and the third outlet tube are no greater than approximately 1 micron in a cross-section diameter.
2 more elements
26-30. (canceled)
A system, comprising:
- an inlet tube;
- a junction fluidically connected to the inlet tube;
- and
- a first outlet tube, a second outlet tube, and a third outlet tube each fluidically connected to the junction,
- wherein the inlet tube, the first outlet tube, the second outlet tube, and the third outlet tube are no greater than approximately 100 nanometers in a cross-section diameter.
2 more elements
32-37. (canceled)
A system, comprising:
- a first source comprising a first inlet;
- a second source comprising a second inlet;
- a third source comprising a third inlet;
- a junction fluidically connecting the first inlet, the second inlet, and the third inlet;
- an outlet tube fluidically connected to the junction;
- and
- a receiving site proximate to a terminal end of the outlet tube,
- wherein the first inlet, the second inlet, the third inlet, and/or the outlet tube have a cross-sectional diameter of no greater than approximately 1 micron.
5 more elements
39-42. (canceled)
Dependencies are inferred from the claim text.