Combination therapy for treating hepatitis b virus infection
AssigneesSanofi, Evotec International GmbH
InventorsAntoine ALAM, Odile BONNIN, Kara CARTER, Julie MONTEGUT, Cendrine LEMOINE, Xavier MARNIQUET
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AssigneesSanofi, Evotec International GmbH
InventorsAntoine ALAM, Odile BONNIN, Kara CARTER, Julie MONTEGUT, Cendrine LEMOINE, Xavier MARNIQUET
Estimating the term…
The invention relates to methods of treating a hepatitis B virus (HBV) infection in a subject in need thereof, comprising administering to the subject a combination of a tumor necrosis factor receptor superfamily (TNFRSF) agonist (e.g., a an agonistic antibody directed against the receptor, a soluble TNFRSF agonist including but not limited to its natural ligand or a fragment of either) and an interferon (IFN) or a functional fragment thereof, to decrease one or more symptoms of HBV infection in the subject are provided.
A method of treating a HBV infection in a subject in need thereof, comprising administering to the subject a combination of a tumor necrosis factor receptor superfamily (TNFRSF) agonist or a functional fragment thereof and an interferon (IFN) agent or a functional fragment thereof.
A pharmaceutical composition comprising:
Dependencies are inferred from the claim text.