RIG-I Agonists and Treatments Using Same
AssigneeYale University
InventorsAkiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova
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Abstract
The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
Claims24
A method of treating, ameliorating, or preventing a cancer in a subject, the method comprising administering to the subject a therapeutically effective amount of a RIG-I agonist.
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A pharmaceutical composition comprising an immune-checkpoint inhibitor and a RIG-I agonist.
Dependencies are inferred from the claim text.