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AssigneeShanghai Ninth People's Hospital, Shanghaijiaotong University School of Medicine
InventorsTao GUO, Xianqun FAN, Yuchen FAN, Li GUO, Iok-Hou Pang, Jiahong WEI
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The present invention provides use of salidroside and a derivative thereof in preparation of an inhibitor medicament for treating diseases, such as opthmalmic fibrosis, caused by abnormalities of extracellular matrix proteins. The present invention treats and prevents diseases associated with ocular fibrosis such as glaucoma, by inhibiting the expression of extracellular matrix proteins in the eye to prevent fibrosis. The present invention further provides use of an inhibitor medicament for treating and preventing diseases, such as opthmalmic fibrosis, caused by abnormalities of extracellular matrix proteins, the inhibitor medicament comprising an effective amount of salidroside and a derivative thereof as active ingredients.
The application of salidroside or derivatives thereof in the preparation of pharmaceutical composition for the treatment of fibrotic ophthalmological disorders related to extracellular matrix protein abnormalities.
A pharmaceutical composition for fibrotic ophthalmological disorders related to extracellular matrix protein abnormalities, comprising an effective amount of salidroside as an active ingredient, in the form of tablets, capsules, pills, oral fluids, injectants, eve drops or eye ointments.
Dependencies are inferred from the claim text.