Aryl hydrocarbon receptor (ahr) modulator compounds

A compound represented by Formula (I), an enantiomer, diastereomer, tautomer, solvate, prodrug or pharmaceutical acceptable salt thereof

• wherein
• A and B are independently selected from 6- to 10-membered mono- or bicyclic aryl and 5- to 10-membered mono- or bicyclic heteroaryl containing 1 to 4 heteroatoms independently selected from N, O and S,
• wherein aryl and heteroaryl are unsubstituted or substituted with 1 to 7 substituents independently selected from the group consisting of halogen, OH, CN, C1-6-alkyl, O—C1-6-alkyl, C(O)ORa, OC(O)Ra, S(O)—C1-6-alkyl, S(O)2—C1-6-alkyl, N(Ra)2, C(O)N(Ra)2, NRaC(O)—C1-6-alkyl, S(O)2N(Ra)2, NRaS(O)2—C1-6-alkyl and C3-6-cycloalkyl,
• wherein the alkyl and cycloalkyl are unsubstituted or substituted with 1 to 3 substituents independently selected from the group consisting of halogen, C1-3-alkyl, halo-C1-3-alkyl, OH, CN and oxo, or
• wherein two substituents on the aryl or heteroaryl group together with the atoms they are attached to may form a 5 to 7-membered saturated or partially unsaturated carbocyclic ring or heterocyclic ring containing 1 to 3 heteroatoms independently selected from O, N and S,
• wherein the carbocyclic or heterocyclic ring is unsubstituted or substituted with 1 to 5 substituents independently selected from the group consisting of halogen, C1-6-alkyl and halo-C1-6-alkyl;
• R1, R2, R3 are each independently selected from hydrogen, halogen, C1-3-alkyl, halo-C1-3-alkyl, OH, O—C1-3-alkyl, and CN;
• Ra is hydrogen or C1-6-alkyl;
• and
• Rb is hydrogen or C1-6-alkyl.