Back to results
US 2021/0259943 A1Published application
Stabilized hyaluronic acid
AssigneeCroma-Pharma GmbH
InventorRobert SACHSENHOFER
Life of this patent
Estimating the term…
Abstract
Sterile hydrogel composition comprising crosslinked hyaluronan, wherein the amount of extractable hyaluronan having a molecular weight of less than 200 kDa is less than 15 wt. % relative to the total amount of hyaluronan.
Claims20
A sterile hydrogel composition comprising crosslinked hyaluronan, wherein the amount of extractable hyaluronan having a molecular weight of less than 200 kDa is less than 15 wt. % relative to the total amount of hyaluronan.
A sterile hydrogel composition comprising crosslinked hyaluronan,
- wherein the crosslinked hyaluronan has structure according to formula I
- HA-L-HA (I),
- wherein each HA stands for hyaluronan or a salt thereof according to formula II
- wherein n is an integer>1 and determines the number of repeats of the repetitive unit of formula II, and L is a linker, which linker is covalently bound to each HA by replacing one OH-moiety in the repetitive unit according to formula II, and
- wherein L is derived from a molecule LH2, wherein the molecule LH2 is a molecule occurring naturally in humans or a conjugate of molecules occurring naturally in humans.
2 more elements
Dependencies are inferred from the claim text.