Methods and systems for digital mammography imaging

A method, comprising:

• receiving an indication of a location of a biopsy target in a contrast-enhanced, dual energy image;
• tagging the location with a marker in a reference dataset used to generate the dual energy image;
• annotating a subsequent image with the marker, a location of the marker in the subsequent image determined via an image registration process with the reference dataset;
• and
• outputting the annotated subsequent image for display on a display device.

An imaging system, comprising:

• an x-ray source in communication with a detector;
• a display device;
• and
• a computing device connected in communication with the display device and the detector, the computing device including a processor and non-transitory memory storing instructions executable by the processor to:
• acquire, with the x-ray source and detector, a first low energy image of a patient and a first high energy image of the patient;
• recombine the first low energy image and the second high energy image to generate a dual energy image;
• output the dual energy image for display on the display device;
• receive a user input indicating a location of a biopsy target on the dual energy image;
• acquire, with the x-ray source and detector, a second low energy image of the patient;
• determine a position of the biopsy target in the second low image based on an image registration process with the first low energy image;
• and
• display, on the display device, the second low energy image and a graphical representation of the position of the biopsy target on the second low energy image.