Biosensor apparatus
AssigneeTaiwan Semiconductor Manufacturing Company, Ltd.
InventorsYu-Jie Huang, Jui-Cheng Huang, Allen Timothy Chang
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Abstract
A biosensor apparatus comprises a biosensor device and a cover that is configured to attach to the biosensor device. The biosensor device includes a surface section that is disposed above the user's skin and an implantable section that is injected into the user's skin. The implantable section includes a bending detector and sensing circuitry. The sensing circuitry includes one or multiples of a biomarker sensor array, a control biomarker sensor array, a temperature sensor, and/or a biofouling detector.
Claims20
A semiconductor biosensor device, comprising:
- a surface section comprising processing circuitry;
- and
- an implantable section for injecting into a user's skin, the implantable section comprising:
- a bending detector;
- and
- a sensing region, the sensing region comprising:
- a biomarker sensor array comprising a plurality of biomarker sensors operable to detect a biomarker;
- a control biomarker sensor array comprising a plurality of biomarker-insensitive sensors;
- a biofouling detector;
- and
- a temperature sensor,
- wherein the sensing region and the bending detector are operably connected to the processing circuitry.
A biosensor apparatus, comprising:
- a semiconductor biosensor device, comprising:
- a surface section comprising processing circuitry and a first contact pad;
- and
- an implantable section for implanting in a user's skin, the implantable section comprising:
- a bending detector;
- and
- a sensing region comprising:
- a plurality of biomarker sensor arrays, each biomarker sensor array comprising a plurality of biomarker sensors operable to detect a biomarker;
- a control biomarker sensor array comprising a plurality of biomarker-insensitive sensors;
- a biofouling detector;
- and
- a temperature sensor,
- wherein the sensing region and the bending detector are operably connected to the processing circuitry;
- and
- a cover operable to attach to the semiconductor biosensor device, the cover comprising:
- a second contact pad electrically connected to the first contact pad;
- and
- an antenna.
A method of operating a semiconductor biosensor device, the method comprising:
- receiving, from a bending detector, a first signal;
- determining a resistance change of the bending detector, the resistance change representing an amount of bend in the bending detector;
- based on the resistance change, determining a first calibration value for a first calibration operation;
- receiving a second signal from a biomarker-sensitive sensor;
- receiving a third signal from a biomarker-insensitive sensor;
- based on the second and the third signals, determining a pH calibration value for a second calibration operation;
- receive, from a biofouling detector, a fourth signal;
- based on the fourth signal, determining an impedance change of the biofouling detector;
- and
- based on the impedance change, determining a second calibration value for a third calibration operation.
Dependencies are inferred from the claim text.