Oxidative stress biomarkers testing in canines
AssigneeHemopet
InventorsWinifred Jean Dodds, Denis Marc Callewaert
Life of this patent
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Abstract
Diagnosing an oxidative stress (OS) in companion animals comprises screening a bodily fluid sample to detect the presence of an OS biomarker, selectively isoprostane and antioxidants, HODE, microRNAs, TAC, GSH, MDA, and TNF-alpha. The sample can be saliva.
Claims19
A method for diagnosing and treating oxidative stress (OS) in a dog comprising the steps of detecting in a saliva sample of a dog the level of at least an OS isoprostane biomarker;
- and diagnosing OS in the dog on an increased quantitative level of the OS isoprostane biomarker, and treating an elevated diagnosed level of the OS isoprostane biomarker with nutritional supplements to lower the elevated level.
A method for diagnosing and treating oxidative stress (OS) in a dog comprising the steps of detecting in a saliva sample of a dog the level of at least one of an isoprostane biomarker and an HODE biomarker, and diagnosing the oxidative stress in the dog on an increased quantitative level of the isoprostane biomarker or the HODE biomarker, and treating an elevated diagnosed level of the isoprostane biomarker with nutritional supplements to lower the elevated level.
A method for diagnosing and treating oxidative stress (OS) in a dog comprising the steps of detecting in a saliva sample of a dog the presence of OS on the quantitative level of an HODE biomarker, diagnosing the oxidative stress in the dog on an increased quantitative level of the HODE biomarker, and treating an elevated diagnosed level of the HODE biomarker to lower the level.
A method for diagnosing and treating oxidative stress (OS) in a dog comprising the steps of detecting in saliva of a dog the presence of an isoprostane OS biomarker based on a quantitative level of the isoprostane biomarker, and diagnosing OS in the dog on an increased quantitative level of the isoprostane biomarker, and treating an elevated diagnosed level of the isoprostane biomarker with nutritional supplements to lower the elevated level.
A device for diagnosing and treating oxidative stress (OS) in a dog comprising a collector tube and connected absorbent pad for location in the mouth of a dog for saliva sample collection, a collection tube, the absorbent pad with saliva being progressively compressible into the collection tube, and detecting in the saliva sample from the collection tube the level of at least an isoprostane biomarker in the dog;
- and diagnosing OS in the dog based on a quantitative level of the isoprostane biomarker.
Dependencies are inferred from the claim text.