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US 2021/0231648 A1Published application
Linker molecule for treating a substrate surface
AssigneeSenzo Health Limited
InventorsAron RACHAMIM, Ron OREN
Life of this patent
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Abstract
A linker molecule and method for treating a substrate surface is provided, which includes a linker molecule with a plurality of moieties capable of resisting non-specific binding of proteins whilst permitting specific binding of a target biomolecule or a biomolecule of interest, including antibodies.
Claims7
A method for depositing a linker molecule providing biomolecule resistance and allowing binding of biomolecules to a substrate, the method comprising the steps of:
- covalently connecting the linker molecule to the substrate through 1-Ethyl-3-(3 dimethylaminopropyl)carbodiimide (EDC) activated coupling;
- and
- deprotecting a hydrazide group of the linker molecule, under mildly acidic conditions, for rendering the hydrazide group available for reaction with an antibody.
Dependencies are inferred from the claim text.