Compositions Comprising Oxo-Derivatives of Fatty Acids and Methods of Making and Using Same
AssigneeDS Biopharma Limited
InventorsMehar Manku, John Climax, David Coughlan
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Abstract
The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.
Claims20
(5Z,8Z,11Z,13E,17Z)-15-oxoicosa-5,8,11,13,17-pentaenoic acid (“15-oxo-EPA”).
A composition comprising about 0.1g to about 4g of (5Z,8Z,11Z,13E,17Z)-15-oxoicosa-5,8,11,13,17-pentaenoic acid (“15-oxo-EPA”).
A pharmaceutical composition comprising (5Z,8Z,11Z,13E,17Z)-15-oxoicosa-5,8,11,13,17-pentaenoic acid (“15-oxo-EPA”) and a pharmaceutically acceptable excipient.
(8Z,11Z,13E)-15-oxoicosa-8,11,13-trienoic acid (“15-oxo-DGLA”).
A composition comprising about 0.1g to about 4g of (8Z,11Z,13E)-15-oxoicosa-8,11,13-trienoic acid (“15-oxo-DGLA”).
A pharmaceutical composition comprising (8Z,11Z,13E)-15-oxoicosa-8,11,13-trienoic acid (“15-oxo-DGLA”) and a pharmaceutically acceptable excipient.
A method of treating and/or preventing fibrosis, inflammation, kidney disease or renal dysfunction in a subject in need thereof, the method comprising administering to the subject a compound, composition, or pharmaceutical composition of any preceding claim.
Dependencies are inferred from the claim text.