US 2021/0228883 A1 · ELECTRICAL STIMULATION MODULATION

Abstract

Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device determines a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a patient. The medical device may control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters. The medical device may further determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of the electrical activity entrained by the entrainment stimulation pulses. The medical device may subsequently control the stimulation generator to generate the desynchronization stimulation pulse(s) according to the second set of stimulation parameters.

Claims25

Dependent claims

A system comprising:

a stimulation generator configured to generate stimulation pulses deliverable via at least one electrical lead comprising at least one electrode;
and
processing circuitry configured to:
determine a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a brain of a patient;
control the stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters;
determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of electrical activity of the brain entrained by the entrainment stimulation pulses, the second set of stimulation parameters being different from the first set of stimulation parameters;
and
subsequent to generating the entrainment stimulation pulses, control the stimulation generator to generate the at least one desynchronization stimulation pulse according to the second set of stimulation parameters.

5 more elements

A method comprising:

determining a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a brain of a patient;
controlling a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters;
determining a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of electrical activity of the brain entrained by the entrainment stimulation pulses, the second set of stimulation parameters being different from the first set of stimulation parameters;
and
subsequent to generating the entrainment stimulation pulses, controlling the stimulation generator to generate the at least one desynchronization stimulation pulse according to the second set of stimulation parameters.

2 more elements

A non-transitory computer-readable storage medium having stored thereon instructions that, when executed, cause one or more processors to:

determine a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a brain of a patient;
control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters;
determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of electrical activity of the brain entrained by the entrainment stimulation pulses, the second set of stimulation parameters being different from the first set of stimulation parameters;
and
subsequent to generating the entrainment stimulation pulses, control the stimulation generator to generate the at least one desynchronization stimulation pulse according to the second set of stimulation parameters.

2 more elements

Dependencies are inferred from the claim text.

Electrical stimulation modulation

Life of this patent

Electrical stimulation modulation

Life of this patent

Abstract

Claims25