Transdermal drug delivery system

A system comprising a patch comprising:

• a tissue contacting side comprising an adhesive layer and an active delivery pad;
• a non-tissue contacting side comprising:
• a biosensor to configure a medical characteristic of a user,
• at least a first electrode and a second electrode wherein each of the first electrode and the second electrode is coupled respectively to a first reservoir containing a first drug and a second reservoir containing a second drug,
• a source of electric power connected in a circuit;
• and
• a microcontroller configured for controlling current flow in said circuit according to a signal from the biosensor to enable plurality of successive doses of said drugs from said reservoirs,
• wherein the active delivery pad at the tissue contacting side allow for an iontophoretic transdermal delivery of the drug to the user through the tissue contacting side.

A system comprising a patch comprising:

• a substrate having a tissue contacting side and a non-tissue contacting side,
• electrodes comprising a first electrode and a second electrode,
• a first reservoir comprising a first drug and a second reservoir comprising a second drug,
• a source of electric power connected in a circuit between the first reservoir and the second reservoir,
• a microcontroller configured for controlling a current flow in the circuit to enable a plurality of successive doses of the first drug and/or the second drug from the first reservoir and/or the second reservoir;
• wherein each of the first electrode and the second electrode are coupled to the first reservoir and the second reservoir respectively,
• wherein the tissue contacting side comprises an adhesive layer that allows transdermal delivery to a patient of the first drug and the second drug, and
• wherein the system is configured to be an automatic and self-controlled transdermal drug delivery system.