Continuous positive airway pressure device for neonates

A continuous positive airway pressure (CPAP) system comprising:

• an inspiratory module comprising
• (i) a first inlet for a compressed oxygen source,
• (ii) a second inlet for an ambient air source,
• (iii) a blender coupled to the first and second inlets to blend compressed oxygen and ambient air from the first and second inlets, respectively,
• (iv) one or more sensors to determine an oxygenation of the blended air, and
• (v) a controller configured to control a ratio of the compressed air provided through the first inlet to the ambient air provided by the second inlet based on the determined oxygenation,
• wherein the ratio is controlled to maintain a desired range of oxygen concentration in the blended air.

A method of generating an airflow for continuous positive airway pressure therapy, the method comprising:

• providing ambient air and compressed oxygen to a blender to generate blended air;
• generating an airflow of the blended air with a blower;
• determining an oxygenation of the blended air;
• and
• controlling a ratio of the compressed oxygen to the ambient air provided to the blender based on the determined oxygenation,
• wherein the ratio is controlled to maintain a desired range of oxygen concentration in the blended air.

A continuous positive airway pressure (CPAP) system comprising:

• an inspiratory portion coupled to a patient interface to provide an airflow with positive pressure to a patient through the patient interface, the inspiratory portion including a first sensor to measure one or more of a pressure or a flow rate of the airflow at the inspiratory portion;
• an expiratory portion coupled to the patient interface to receive air exhaled from the patient, the expiratory portion including a second sensor for measuring one or more of a pressure or a flow rate of the air exhaled at the expiratory portion;
• and
• a controller configured to (i) determine a pressure at the patient interface based on the measured one or more of the pressure or the flow rate of the airflow at the inspiratory portion and the measured one or more of the pressure or the flow rate of the air exhaled at the expiratory portion and (ii) modify the airflow provided by the inspiratory portion based on the determined pressure at the patient interface.

A method of generating an airflow for continuous positive airway pressure therapy, the method comprising:

• measuring one or more of a pressure or a flow rate of an airflow generated at an inspiratory portion of a continuous positive airway pressure (CPAP) system;
• measuring one or more of a pressure or a flow rate of air exhaled and received at an expiratory portion of the CPAP system;
• determining a pressure at a patient interface coupled to the CPAP system based on the measured one or more of the pressure or the flow rate of the airflow at the inspiratory portion and the measured one or more of the pressure or the flow rate of the air exhaled at the expiratory portion;
• and
• modifying the airflow provided by the inspiratory portion based on the determined pressure at the patient interface.

A continuous positive airway pressure (CPAP) system comprising:

• an inspiratory portion coupled to a patient interface to provide an airflow with positive pressure to a patient through the patient interface;
• an expiratory portion coupled to the patient interface to receive air exhaled from the patient;
• a controller coupled to the inspiratory and expiratory portions to receive one or more sensor measurements therefrom;
• and
• a user interface comprising a display,
• wherein the controller is configured to cause the display to provide a visual alert to one or more of a user or the patient in response to the received one or more sensor measurements.

A method of continuous positive airway pressure therapy, the method comprising:

• providing an airflow with positive pressure to a patient;
• receiving air exhaled from the patient;
• receiving one or more sensor measurements of one or more of the provided airflow or the received air exhaled;
• providing a visual alert to one or more of a user or the patient in response to the received one or more sensor measurements.