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AssigneeThe University of Hong Kong
InventorsWeiping WANG, Wen LYU
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The field of various phototriggered drug release and photoreactions, including reactions generally based on triplet-triplet energy transfer with light excitation at long wavelengths. Systems and methods for absorbing energy in a photosensitizer, and methods for making or using such systems, kits including such systems. The systems and methods comprise transferring that energy by triplet-triplet energy transfer to cleave a cleavable or other active moiety, for instance, in order to cause the release of a releasable moiety. In some cases, these may be contained within a suitable carrier material, for example, a particle or a micelle. Such systems and methods may be used in a variety of applications, including various biological or physical applications. For example, such systems and methods may be useful for delivering drugs or other releasable moieties to regions of a subject.
A composition, comprising:
A composition, comprising:
A method comprising transferring energy directly from a photosensitizer to an active moiety via triplet-triplet energy transfer causing a chemical reaction in the active moiety wherein the energy is not transferred via an annihilator.
A method comprising applying to a subject, a composition comprising a photosensitizer to transfer triplet-triplet energy from the photosensitizer to a cleavable moiety to cause cleavage of the cleavable moiety;
Dependencies are inferred from the claim text.