Back to results
US 2021/0228623 A1Published application
Method of administration and treatment
AssigneeDyve Biosciences, Inc.
InventorRyan Beal
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeDyve Biosciences, Inc.
InventorRyan Beal
Estimating the term…
Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.
A method of treating a melasma, comprising administering a transdermal formulation comprising a buffering agent to a patient suffering from a melasma, wherein the transdermal formulation reduces the level of brown to gray-brown at the site of melasma by at least 50%, wherein the buffering agent consists of sodium bicarbonate.
A method of treating a melasma, comprising administering a transdermal formulation comprising a buffering agent to a patient suffering from a melasma, wherein the transdermal formulation reduces the level of brown to gray-brown at the site of melasma by at least 50%, wherein the buffering agent consists of sodium carbonate.
Dependencies are inferred from the claim text.