A Manufacturing Process for 2-Nitroimino Heterocyclic Compounds
AssigneeUpl Ltd
InventorsChandrasekhar Dayal Mudaliar, Sadanand Sadashiv Pandit, Jaidev Rajnikant Shroff, Vikram Rajnikant Shroff
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Abstract
The present invention relates to a process for manufacture of 2-nitroimino heterocyclic compounds and intermediates thereof. More particularly, the present invention relates to a convenient manufacturing process for preparation of 2-nitroimino imidazolidine compounds.
Claims14
A process for preparation of nitroimino heterocyclic compounds of Formula B:
- comprising reacting a compound of Formula II;
- with a compound of Formula III
- wherein R represent hydrogen or an optionally substituted lower alkyl of 1 to 4 carbon atoms;
- and n is 2, 3 or 4;
- wherein said compound of formula II is reacted with said compound of formula III without isolating or separating the compound of formula II from a mixture comprising the reaction product of a reaction of a compound of formula I with an acid
A one pot process for preparing a nitroimino heterocyclic compound of Formula B
- comprising:
- a) reacting a compound of Formula I with an acid to form a compound of Formula II;
- and
- b) reacting compound of Formula II with a compound of Formula III to give a compound of Formula B, wherein compound of formula II is not isolated,
- and wherein R represent hydrogen or an optionally substituted lower alkyl of 1 to 4 carbon atoms and n is 2, 3 or 4.
A process for preparing nitroimino heterocyclic compound of Formula IV:
- said process comprising reacting a compound of Formula II with ethylene diamine to obtain a compound of formula IV:
- wherein said compound of formula II is reacted with ethylene diamine without isolating or separating the compound of formula II from a mixture comprising the reaction product of a reaction of a compound of formula I with an acid:
A one pot process for preparing compound of Formula IV,
- comprising:
- a) treating a compound of Formula I with sulfuric acid to form a compound of Formula II;
- and
- b) treating a compound of Formula II with ethylene diamine to give a compound of Formula IV, wherein compound of Formula II is not isolated.
A process for preparing imidacloprid comprising reacting a compound of Formula IV with a compound of Formula V to obtain imidacloprid;
A one pot process for preparing imidacloprid comprising:
- a) reacting a compound of Formula I with sulfuric acid to give a compound of Formula II;
- b) reacting a compound of Formula II with ethylene diamine to give a compound of Formula IV, wherein compound of formula II is not isolated;
- c) reaction of compound of Formula IV with compound of Formula V to obtain imidacloprid.
Dependencies are inferred from the claim text.